Bromine → HCID 21319211, compound

HRID 262451Notes

Reaction equation

HRID 262451 reaction equation
[C:1]([O:4][CH2:5][C:6]([CH3:19])([CH3:18])[C:7](=[O:17])[CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][CH:11]=1)(=[O:3])[CH3:2].[Br:20]Br>C(Cl)(Cl)(Cl)Cl>[C:1]([O:4][CH2:5][C:6]([CH3:19])([CH3:18])[C:7](=[O:17])[CH:8]([Br:20])[O:9][C:10]1[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][CH:11]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24408BromineHCID 23350027HCID 23350027, compound

Product 1

HCID 21319211HCID 21319211, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

56.9 g (0.2 mol) of 4-acetoxy-1-(4-chlorophenoxy)-3,3-dimethyl-butan-2-one were dissolved in 350 ml of carbon tetrachloride. 10.3 g (0.2 mol) of bromine were added dropwise, at room temperature, in such a way that the bromine was steadily consumed. Thereafter, the mixture was stirred for 30 minutes at room temperature. After distilling off the solvent in vacuo, 4-acetoxy-1-bromo-1-(4-chlorophenoxy)-3,3-dimethyl-butan-2-one was obtained quantitatively and could be directly reacted further. ##STR11##

Workup

  1. customin such a way that the bromine was steadily consumed
  2. distillationAfter distilling off the solvent in vacuo

Sources & evidence

ORD record
ord-6a73d5c972af4dea86353396db3d4cf8
Source dataset
uspto-grants-1979_05
Patent number
US04154842

Reaction notes

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