Isopropylamine → HCID 21319079, compound

HRID 262487Notes

Reaction equation

HRID 262487 reaction equation
[CH3:1][N:2]1[C:11]([CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH:22]3[O:24][CH2:23]3)=[CH:16][CH:15]=2)=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:25][CH3:26])=[CH:7][CH:8]=2)[C:3]1=[O:27].[CH:28]([NH2:31])([CH3:30])[CH3:29]>>[CH3:1][N:2]1[C:11]([CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH:22]([OH:24])[CH2:23][NH:31][CH:28]([CH3:30])[CH3:29])=[CH:16][CH:15]=2)=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:25][CH3:26])=[CH:7][CH:8]=2)[C:3]1=[O:27]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 21319023HCID 21319023, compound

Product 1

HCID 21319079HCID 21319079, compoundYield 77%

Procedure

2-Methyl-3-[4-(2-hydroxy-3-isopropylamino-propoxy)-phenethyl]-7-methoxy-isoquinolin-1(2H)-one was prepared analogous to Example 1b from 2-methyl-3-[4-(2,3-epoxypropoxy)-phenethyl]-7-methoxy-isoquinolin-1(2H)-one and isopropylamine.

Sources & evidence

ORD record
ord-fa486892e9ce4fa9b8d4214e4a739925
Source dataset
uspto-grants-1979_05
Patent number
US04154837

Reaction notes

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