4-Methoxy-N-methylbenzeneethanamine → HCID 21319055, compound

HRID 262491Notes

Reaction equation

HRID 262491 reaction equation
[CH3:1][N:2]1[C:11]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][Cl:22])=[CH:14][CH:13]=2)=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:23][CH3:24])=[CH:7][CH:8]=2)[C:3]1=[O:25].[CH3:26][O:27][C:28]1[CH:37]=[CH:36][C:31]([CH2:32][CH2:33][NH:34][CH3:35])=[CH:30][CH:29]=1>>[ClH:22].[CH3:1][N:2]1[C:11]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][N:34]([CH2:33][CH2:32][C:31]3[CH:36]=[CH:37][C:28]([O:27][CH3:26])=[CH:29][CH:30]=3)[CH3:35])=[CH:14][CH:13]=2)=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:23][CH3:24])=[CH:7][CH:8]=2)[C:3]1=[O:25]

Participants

3

Reactant 2

HCID 1047354-Methoxy-N-methylbenzeneethanamineHCID 21319029HCID 21319029, compound

Product 1

HCID 21319055HCID 21319055, compoundYield 75%

Procedure

2-Methyl-3-[4-(3-(N-4-methoxyphenethyl-N-methyl-amino)-propoxy)-phenyl]-7-methoxy-isoquinolin-1(2H)-one hydrochloride was prepared analogous to Example 3b from 2-methyl-3-[4-(3-chloropropoxy)-phenyl]-7-methoxy-isoquinoline-1(2H)-one and N-b 4-methoxyphenethyl-N-methyl-amine.

Sources & evidence

ORD record
ord-b45a0442a0c5471fbe7e428b9e0c2906
Source dataset
uspto-grants-1979_05
Patent number
US04154837

Reaction notes

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