Isopropylamine → HCID 13688287, compound

HRID 262492Notes

Reaction equation

HRID 262492 reaction equation
[CH3:1][N:2]1[C:11]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH:20]3[O:22][CH2:21]3)=[CH:14][CH:13]=2)=[CH:10][C:9]2[N:8]=[CH:7][CH:6]=[CH:5][C:4]=2[C:3]1=[O:23].[CH:24]([NH2:27])([CH3:26])[CH3:25]>>[CH3:1][N:2]1[C:11]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH:20]([OH:22])[CH2:21][NH:27][CH:24]([CH3:26])[CH3:25])=[CH:14][CH:13]=2)=[CH:10][C:9]2[N:8]=[CH:7][CH:6]=[CH:5][C:4]=2[C:3]1=[O:23]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 21319028HCID 21319028, compound

Product 1

HCID 13688287HCID 13688287, compoundYield 92%

Procedure

6-Methyl-7-[4-(2-hydroxy-3-isopropylamino-propoxy)-phenyl]-1,6-naphthyridin-5(6H)-one was prepared analogous to Example 1b from 6-methyl-7-[4-(2,3-epoxypropoxy)-phenyl]-1,6-naphthyridin-5(6H)-one and isopropylamine.

Sources & evidence

ORD record
ord-abac853ec1794d13b822708b6e416059
Source dataset
uspto-grants-1979_05
Patent number
US04154837

Reaction notes

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