Ethanol → Ethyl 3-quinolinepropionate

HRID 262510Notes

Reaction equation

HRID 262510 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]([CH:11]=[CH:12][C:13]([O-:15])=[O:14])[CH:2]=1.[CH2:16](O)[CH3:17]>[Pd]>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]([CH2:11][CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:2]=1

Participants

4

Reactant 2

HCID 702EthanolHCID 784346313-Quinolineacrylate

Product 1

HCID 14338577Ethyl 3-quinolinepropionate

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

3-quinolineacrylate (51.68 g) was dissolved in ethanol (170 ml) and hydrogenated at 37° and a pressure of 50 psi using 10% Palladium on charcoal to give ethyl 3-quinolinepropionate.

Sources & evidence

ORD record
ord-e50adda9c1654e32ad480b69b3ba384f
Source dataset
uspto-grants-1979_05
Patent number
US04154834

Reaction notes

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