反应详情

An intimate mixture of 5-(3-pyridylmethyl)-2-methylthio-4-pyrimidone and 3-(5-methyl-4-imidazolylmethylthio)propylamine is heated at 130°-135° for 7 hours. The cool mixture is triturated with hot water and treated with dilute ethanolic HCl to give the trihydrochloride of the title compound.

1. temperatureis heated at 130°-135° for 7 hours
2. customThe cool mixture is triturated with hot water
3. additiontreated with dilute ethanolic HCl