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Hydrochloric Acid → 2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | 8,9-dihydro-3-nitro-5H-benzocyclohepten-5-one | HCID 20094732 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride | HCID 86736536 | — |
反応手順
Using the procedure of Example 1, 3-nitro-8,9-dihydro [5H] benzocycloheptene-5-one and dimethylamine were reacted to obtain a non-salified product which was treated in ethyl acetate with a solution of ethyl acetate saturated with gaseous hydrogen chloride to obtain a product which was crystallized from isopropanol to obtain 2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride melting at 202° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04154852 |
| 出典データセット | uspto-grants-1979_05 |
| ORD ID | ord-90242655c5d1464691f6d4744eae6f66 |
| 出典メモ | uspto-grants-1979_05 |