Methacrylic Acid → 3-(Acetylthio)-2-methylpropanoic acid

HRID 262552ノート

反応式

HRID 262552 の反応式
[C:1]([OH:4])(=[S:3])[CH3:2].[C:5]([OH:10])(=[O:9])[C:6]([CH3:8])=[CH2:7]>>[C:1]([S:3][CH2:7][CH:6]([CH3:8])[C:5]([OH:10])=[O:9])(=[O:4])[CH3:2]

参加物

3

反応物 2

HCID 4093Methacrylic Acid2 回HCID 178418634HCID 178418634、化合物

生成物 1

HCID 1180733-(Acetylthio)-2-methylpropanoic acid

実験手順

A mixture of thioacetic acid (50 g.) and methacrylic acid (40.7 g.) is heated on the steam bath for one hour and then stored at room temperature for 18 hours. After confirming by nmr spectroscopy that complete reaction of the methacrylic acid has been achieved, the reaction mixture is distilled in vacuo and the desired 3-acetylthio-2-methylpropanoic acid is separated in the fraction with boiling point 128.5°-131° (2.6 mmHg.), yield 64 g.

後処理

  1. temperatureis heated on the steam bath for one hour
  2. distillationthe reaction mixture is distilled in vacuo
  3. customthe desired 3-acetylthio-2-methylpropanoic acid is separated in the fraction with boiling point 128.5°-131° (2.6 mmHg.), yield 64 g

出典と根拠

ORDレコード
ord-32b82272b1be4e76a3a668cd3e005bfe
出典データセット
uspto-grants-1979_05
特許番号
US04154840

反応ノート

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