HCID 13208371, compound → HCID 54307843, compound

HRID 262569Notes

Reaction equation

HRID 262569 reaction equation
[SH:1][CH2:2][CH:3]([CH3:14])[C:4]([N:6]1[CH2:13][CH2:12][CH2:11][C@H:7]1[C:8]([NH2:10])=[O:9])=[O:5].[CH2:15](OC(=O)[C@@H]1CCCN1C(=O)CCS)C>>[CH3:15][S:1][CH2:2][CH:3]([CH3:14])[C:4]([N:6]1[CH2:13][CH2:12][CH2:11][C@H:7]1[C:8]([NH2:10])=[O:9])=[O:5]

Participants

3

Reactant 2

HCID 13208371HCID 13208371, compoundHCID 53898049HCID 53898049, compound

Product 1

HCID 54307843HCID 54307843, compound

Procedure

By substituting 1-(3-mercapto-2-methylpropanoyl)-L-proline amide for the 1-(3-mercaptopropanoyl)-L-proline ethyl ester in the Procedure B of Example 80 and eliminating the saponification step, 1-(3-methylthio-2-methylpropanoyl)-L-proline amide is obtained.

Sources & evidence

ORD record
ord-00d28e84223649dba931f9f291727ca3
Source dataset
uspto-grants-1979_05
Patent number
US04154840

Reaction notes

Loading…