N-(2-pyrimidylmethyl)ethylenediamine → HCID 178512213, compound

HRID 262631Notes

Reaction equation

HRID 262631 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[CH2:7][NH:8][CH2:9][CH2:10][NH2:11].CS[C:14](=[NH:19])[NH:15][N+:16]([O-:18])=[O:17]>>[N+:16]([NH:15][C:14]([NH:11][CH2:10][CH2:9][NH:8][CH2:7][C:2]1[N:3]=[CH:4][CH:5]=[CH:6][N:1]=1)=[NH:19])([O-:18])=[O:17]

Participants

3

Reactant 2

HCID 20557649N-(2-pyrimidylmethyl)ethylenediamineHCID 135927615N-Nitro-S-methylisothiourea

Product 1

HCID 178512213HCID 178512213, compound

Procedure

Reaction of N-(2-pyrimidylmethyl)ethylenediamine with S-methyl-N-nitroisothiourea by the procedure of Example 2(ii) gives N-nitro-N'-[2-(2-pyrimidylmethylamino)-ethyl]guanidine. Similarly, from the same starting material, according to the procedure of Example 2(iii), there is produced N-methyl-N'-nitro-N"-[2-(2-pyrimidylmethylamino)ethyl]guanidine.

Sources & evidence

ORD record
ord-a07416b0a9ca4f9eb7189ae55b543501
Source dataset
uspto-grants-1979_05
Patent number
US04154844

Reaction notes

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