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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 262637Generated: October 25, 2026

Ethyl isothiocyanate → N-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea

https://huagongshe.com/reaction/262637

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl isothiocyanateHCID 10966—
ReactantN-(pyrazinylmethyl)ethylenediamineHCID 13910894—
ProductN-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thioureaHCID 20567640—

Reaction Steps

Reacting N-(2-pyrazinylmethyl)ethylenediamine with ethyl isothiocyanate by the procedure of Example 3 and chromatographing gives N-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea. Reacting this thiourea with lead cyanamide by the procedure of Example 3 gives N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]-guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04154844
Source datasetuspto-grants-1979_05
ORD IDord-20b3c5232b844542baa4cae791ce9a55
Source noteuspto-grants-1979_05