HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-{[(1,2-Thiazol-3-yl)methyl]sulfanyl}ethan-1-amine → N-[2-(3-isothiazolylmethylthio)ethyl)-N'-methyl-N"-nitroguanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-{[(1,2-Thiazol-3-yl)methyl]sulfanyl}ethan-1-amine | HCID 12951537 | — |
| Reactant | N-Nitro-S-methylisothiourea | HCID 135927615 | — |
| Reactant | 1,2-Dimethyl-3-nitroisothiourea | HCID 136227017 | — |
| Reactant | HCID 178512219 | HCID 178512219 | — |
| Product | N-[2-(3-isothiazolylmethylthio)ethyl)-N'-methyl-N"-nitroguanidine | HCID 136353517 | — |
Reaction Steps
Reacting 3-[(2-aminoethyl)thiomethyl]isothiazole with S-methyl-N-nitroisothiourea by the procedure of Example 2(ii) gives N-[2-(3-isothiazolylmethylthio)ethyl]-N'-nitroguanidine and reaction of the same starting material with N,S-dimethyl-N'-nitroisothiourea by the procedure of Example 2(iii) gives N-[2-(3-isothiazolylmethylthio)ethyl]-N'-methyl-N"-nitroguanidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04154844 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-80051e56bfcd49cbbcf9c53f094fd0ea |
| Source note | uspto-grants-1979_05 |