2,5-Bis(2,2,2-trifluoroethoxy)nitrobenzene → 2,5-Bis(trifluoroethoxy)aniline

HRID 262741Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 262741
[F:1][C:2]([F:21])([F:20])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][C:13]([F:16])([F:15])[F:14])=[CH:7][C:6]=1[N+:17]([O-])=O.[H][H]>[Ni].C(O)C>[F:1][C:2]([F:20])([F:21])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][C:13]([F:16])([F:15])[F:14])=[CH:7][C:6]=1[NH2:17]

Komponenten

5

Edukt 2

HCID 133704322,5-Bis(2,2,2-trifluoroethoxy)nitrobenzeneHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 133704342,5-Bis(trifluoroethoxy)aniline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

a mixture of 59 g. (0.185 mole) of 2,5-bis-(2,2,2-trifluoroethoxy)nitrobenzene, about 15 g. of Raney nickel and 1200 ml. of ethanol is hydrogenated by shaking on a Parr hydrogenation apparatus with a hydrogen pressure of 40 to 50 p.s.i. for about five hours. The mixture is filtered, and the filtrate is evaporated to a liquid residue. The residue is distilled to provide 2,5-bis(2,2,2-trifluoroethoxy)aniline as a clear, colorless liquid, b.p. 95°-98° C/0.35 mm Hg.

Aufarbeitung

  1. additiona mixture of 59 g
  2. filtrationThe mixture is filtered
  3. customthe filtrate is evaporated to a liquid residue
  4. distillationThe residue is distilled

Quellen und Nachweise

ORD-Eintrag
ord-239d16a9181e44d5aa2004932f8352a6
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04154941

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