反应详情

A mixture of 5.85 g. of methyl 3-(2,6-dichlorobenzylidene)thiocarbazimidate hydriodide, 3.24 g. of 3-(aminomethyl)pyridine and 25 ml. of absolute ethanol is heated under reflux for 24 hours and diluted while hot with 75 ml. of water. After cooling, an oil separates and crystallizes. The mixture is chilled overnight and the crystals are separated and recrystallized from 100 ml. of 50% aqueous ethanol to give the desired product as pale yellow crystals, m.p. 148°-151° C.

1. additionA mixture of 5.85 g
2. temperatureunder reflux for 24 hours
3. additiondiluted while hot with 75 ml
4. temperatureAfter cooling
5. customan oil separates and crystallizes
6. temperatureThe mixture is chilled overnight
7. customthe crystals are separated
8. customrecrystallized from 100 ml