反应详情

A mixture of 2.93 g. of 1-amino-3-(2-pyridylmethyl)guanidine hydriodide and 1.34 g. of 2,6-dimethylbenzaldehyde [G. Lock and K. Schmidt, J. Prakt. Chem., 140, 229 (1934)] is dissolved in 5 ml. of glacial acetic acid at 100° C. After 2 hours the solidified reaction is triturated with water and filtered. Crystallization from absolute ethanol gives the desired product as colorless needles, m.p. 184°-186° C.

1. additionA mixture of 2.93 g
2. customat 100° C
3. customAfter 2 hours the solidified reaction
4. customis triturated with water
5. filtrationfiltered
6. customCrystallization from absolute ethanol