Hydrochloric Acid → 4-(13,13-Dimethyltetradecyl)aminobenzoic acid

HRID 262923ノート

反応式

HRID 262923 の反応式
[CH3:1][C:2]([CH3:28])([CH3:27])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][NH:15][C:16]1[CH:26]=[CH:25][C:19]([C:20]([O:22]CC)=[O:21])=[CH:18][CH:17]=1.C(O)C.[OH-].[K+].Cl>O>[CH3:1][C:2]([CH3:28])([CH3:27])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][NH:15][C:16]1[CH:17]=[CH:18][C:19]([C:20]([OH:22])=[O:21])=[CH:25][CH:26]=1

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14797Potassium HydroxideHCID 20437372Ethyl 4-(13,13-dimethyltetradecyl)aminobenzoate

生成物 1

HCID 204373434-(13,13-Dimethyltetradecyl)aminobenzoic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A solution of 5 g. of ethyl 4-(13,13-dimethyltetradecyl)aminobenzoate in 75 ml. 95% ethanol is saponified with 2.5 g. of 85% potassium hydroxide by refluxing for 5 hours. The warm solution is diluted with 150 ml. water and adjusted to pH 5 with 37% hydrochloric acid. The precipitate is filtered, washed with water, dried in vacuo and crystallized from acetic acid to yield the title compound as a creamcolored, amorphous solid.

後処理

  1. additionThe warm solution is diluted with 150 ml
  2. filtrationThe precipitate is filtered
  3. washwashed with water
  4. customdried in vacuo
  5. customcrystallized from acetic acid

出典と根拠

ORDレコード
ord-6c595d2b7f0d44e49a92bc2a0a852d0d
出典データセット
uspto-grants-1979_05
特許番号
US04154756

反応ノート

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