Aluminium lithium hydride → HCID 21317477, compound

HRID 262948Notes

Reaction equation

HRID 262948 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].[OH:7][C:8]1[CH:13]=[CH:12][C:11]([S:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([N:21]2[CH2:26][CH2:25][O:24][CH2:23][CH2:22]2)=O)=[CH:10][CH:9]=1>>[OH:7][C:8]1[CH:13]=[CH:12][C:11]([S:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][N:21]2[CH2:22][CH2:23][O:24][CH2:25][CH2:26]2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 21317467HCID 21317467, compound

Product 1

HCID 21317477HCID 21317477, compound

Procedure

Lithium aluminum hydride reduction of the amide was accomplished according to the procedure of Example 5, giving 26.1 g of the 4-(5-(4-hydroxyphenylthio)pentyl)morpholine as a white solid. Recrystallization from ethanol gave the product as white crystals, mp 168°-171° C.

Sources & evidence

ORD record
ord-d98aa4534d214e52a9aee06c31b186c1
Source dataset
uspto-grants-1979_05
Patent number
US04155907

Reaction notes

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