Ammonia → HCID 21318029, compound

HRID 263042Notes

Reaction equation

[C:1]([C:9]1[C:13]([CH:14]2[CH2:16][CH2:15]2)=[CH:12][S:11][C:10]=1[NH:17][C:18](=[O:21])[CH2:19]Br)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:22]>>[NH2:22][CH2:19][C:18]([NH:17][C:10]1[S:11][CH:12]=[C:13]([CH:14]2[CH2:16][CH2:15]2)[C:9]=1[C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[O:21]

Participants

Reactant 2

HCID 222Ammonia

HCID 21318031HCID 21318031, compound

Product 1

HCID 21318029HCID 21318029, compound

Procedure

reacting the 3-benzoyl-2-(α-bromoacetamido)-4-cyclopropylthiophene with ammonia to obtain 2-(α-aminoacetamido)-3-benzoyl-4-cyclopropylthiophene (V),

Sources & evidence

ORD record: ord-90b52cc722c84bc5a6df185d4c607968
Source dataset: uspto-grants-1979_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04156009

Reaction notes

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