Sodium borohydride → HCID 20343015, compound

HRID 263107Notes

Reaction equation

HRID 263107 reaction equation
[CH3:1][N:2]([CH3:25])[CH:3]([CH3:24])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][C:7]=1[CH:14]=[N:15][CH2:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[BH4-].[Na+]>CO>[CH3:25][N:2]([CH3:1])[CH:3]([CH3:24])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][C:7]=1[CH2:14][NH:15][CH2:16][CH2:17][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 20343016HCID 20343016, compound

Product 1

HCID 20343015HCID 20343015, compoundYield 74.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

N-[[2-[2-(Dimethylamino)propoxyl]-5-methoxyphenyl]methylene]benzeneethanamine (39.5 g) is reduced with 13.0 g of sodium borohydride in 200 ml of methanol following the procedure described in Example 1C yielding 29.7 g of the title compound, boiling point 205°-210° C. at 0.4-0.5 mm of Hg.

Sources & evidence

ORD record
ord-54eb44b3cf084fd2a59e92a3ba1bb1c1
Source dataset
uspto-grants-1979_05
Patent number
US04156079

Reaction notes

Loading…