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HRID263132

反应详情

EQUATION

反应方程式

HRID 263132 的结构方程式

REACTANTS

反应物

3
结构：N
HCID222

Ammonia gas

H3N

结构：[Li]
HCID3028194

Lithium

Li

结构：CC1=CC2(CC(C)(C)C1=O)OCCO2
HCID11769425

1,4-Dioxaspiro[4.5]dec-6-en-8-one, 7,9,9-trimethyl-

C11H16O3

PRODUCTS

生成物

1
结构：CC(C#CC1(O)C(C)=CC2(CC1(C)C)OCCO2)=CCO
HCID131711512

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].[Fe+3]
催化剂HCID25251

Ferric nitrate

FeN3O9

结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

Keto-α-isophorone is acetalized. The resulting 7,9,9-trimethyl-1,4-dioxaspiro[4,5]dec-6-en-8-one is condensed with trans-1-hydroxy-3-methyl-pent-2-en-4-yne in the presence of lithium in liquid ammonia and iron-(III) nitrate in ether to give rac. 8-(5-hydroxy-3-methyl-pent-3-en-1-yn-1-yl)-7,9,9-trimethyl-1,4-dioxaspiro[4,5]dec-6-en-8-ol (XVI).