Water → HCID 53987691, compound

Participants

Reaction Conditions

Reaction Steps

13.5 g of the ketoaldehyde of formula XII obtained in Example 20 are dissolved in 100 ml of pyridine. 10 g of phenoxyacetic acid chloride are added dropwise to the solution at 0° C. The mixture is stirred for 1 hour at 0° C. and then poured into water and extracted with diethyl ether. The ether extract is washed with 5% strength aqueous sulfuric acid and then with water. The 5-[2,6,6-trimethyl-3-oxo-4(S)-(phenoxyacetoxy)-cyclohex-1-en-1-yl]-3-methyl-penta-2-en-4-yn-1-al (XIV) isolated from the extract is further reacted as follows:

Provenance & Evidence