Water → HCID 54289147, compound

Participants

Reaction Steps

13 grams of 5-[2,6,6-trimethyl-oxo-4(S)-hydroxy-cyclohex-1-en-1-yl]-3-methyl-penta-2,4-dien-1-al (XIII) are dissolved in 200 ml of diethyl ether. 20 ml of pyridine are added to the solution at 0° C. and 12 g of chloroacetic acid chloride are then added dropwise. The mixture is stirred for 1 hour and then poured into water and extracted with diethyl ether. The 5-[2,6,6-trimethyl-3-oxo-4(S)-(chloroacetoxy)-cyclohex-1-en-1-yl]-3-methyl-penta-2,4-dien-1-al is isolated from the ether extract (IIA).

Provenance & Evidence