HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → N-Cyano-N'-methyl-N"-[2-((4-methoxy-2-pyridyl)methylthio)ethyl]guanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 20474239 | HCID 20474239 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-Cyano-N'-methyl-N"-[2-((4-methoxy-2-pyridyl)methylthio)ethyl]guanidine | HCID 178484980 | — |
Reaction Steps
Methylamine in ethanol (33%, 20 cc) was added to a stirred solution of N-cyano-N'-[2-((4-methoxy-2-pyridyl)methylthio)ethyl]-S-methylisothiourea (3.56 g) in ethanol (25 cc) at 35°, and the mixture was left to stand overnight. Nitrogen was bubbled through the solution and the crystals were filtered off to give the title product, (2.74 g) m.p. 121°-122°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04156727 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-e46bc7bd66e84f538924ed4a7e3f7a0e |
| Source note | uspto-grants-1979_05 |