反应详情

温度

140 °C

A mixture of 0.2 mol (31.0 g) of 3-methyl-4-fluoronitrobenzene and 0.7 mol (70.7 g) of tetrahydrofurfurylamine is heated for one hour in an oil bath at 140° C. The reaction mixture is then poured into 400 g of ice-cooled water. The expected product rapidly crystallises; after it has been filtered off, washed with water, recrystallised from ethanol and dried in vacuo, it melts at 60° C.

1. customThe expected product rapidly crystallises
2. filtrationafter it has been filtered off
3. washwashed with water
4. customrecrystallised from ethanol
5. customdried in vacuo, it melts at 60° C.