HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl bromoacetate → 4-(S)-Isopropyl-3-[2-(R)-tert-butoxycarbonylmethyl-1-oxo-4-phenylbutyl]-2-oxazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | 4-(S)-Isopropyl-3-(1-oxo-4-phenylbutyl)-2-oxazolidinone | HCID 11807933 | — |
| Product | 4-(S)-Isopropyl-3-[2-(R)-tert-butoxycarbonylmethyl-1-oxo-4-phenylbutyl]-2-oxazolidinone | HCID 53800325 | — |
Reaction Steps
Following the procedure described in Referential Example 4, but using 4-(S)-isopropyl-3-(1-oxo-4-phenylbutyl)-2-oxazolidinone (8.83 g), prepared in Referential Example 91, and tert-butyl bromoacetate (25.0 ml), there was obtained the desired compound (7.35 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05643908 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-406e73bca57c48adbb1f3ffb063a837e |
| Source note | uspto-grants-1997_07 |