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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 263612Generated: October 25, 2026

3,4-Diethoxybenzene-1-carbothioamide → 2-(3,4-Diethoxyphenyl)-4-(5-carboxy-3-thienyl)thiazole

https://huagongshe.com/reaction/263612

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Diethoxybenzene-1-carbothioamideHCID 7745250—
Reactant5-Ethoxycarbonyl-3-(alpha-bromoacetyl)thiopheneHCID 18707255—
Product2-(3,4-Diethoxyphenyl)-4-(5-carboxy-3-thienyl)thiazoleHCID 18707316—

Reaction Steps

5-Ethoxycarbonyl-3-(α-bromoacetyl)thiophene and 3,4-diethoxythiobenzamide were subjected to the same reaction as in Example 1 and then to the same hydrolysis as in Example 147 to obtain 2-(3,4-diethoxyphenyl)-4-(5-carboxy-3-thienyl)thiazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05643932
Source datasetuspto-grants-1997_07
ORD IDord-46170fd8def64cc7b76360f6e197491b
Source noteuspto-grants-1997_07