化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl N-methylaminoacetate hydrochloride → N-Methyl-N-[2-(2,4,6-trimethylphenyl)-2-cyanovinyl]-glycine ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl N-methylaminoacetate hydrochloride | HCID 171173 | — |
| 反応物 | 3-Oxo-2-(2,4,6-trimethyl-phenyl)-propionitrile | HCID 22474397 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | N-Methyl-N-[2-(2,4,6-trimethylphenyl)-2-cyanovinyl]-glycine ethyl ester | HCID 54495113 | — |
反応手順
A mixture of a-formyl-2,4,6 trimethylphenylacetonitrile (4.5 g, 24 mmol) and sarcosine ethyl ester hydrochloride (3.7 g, 24 mmol) in 100 mL of benzene was refluxed in a Dean-Stark apparatus for 16 h. The solvent was removed in vacuo to afford N-Methyl-N-[2-(2,4,6-trimethylphenyl)-2-cyanovinyl]-glycine ethyl ester as a pale yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05644057 |
| 出典データセット | uspto-grants-1997_07 |
| ORD ID | ord-5e47cd794cfa43fabfef38e67bdb4b46 |
| 出典メモ | uspto-grants-1997_07 |