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HRID263876

反应详情

EQUATION

反应方程式

HRID 263876 的结构方程式

REACTANTS

反应物

1
结构：CC(=O)OC[C@H]1O[C@@H](n2c(Cl)nc3cc(Br)c(Br)cc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O
HCID10555022

未命名化合物

PRODUCTS

生成物

1
结构：OC[C@H]1O[C@@H](n2c(Cl)nc3cc(Br)c(Br)cc32)[C@H](O)[C@@H]1O
HCID469424

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO.N
溶剂HCID21705897

未命名化合物

PROCEDURE

实验过程

A solution of 569 mg (1 mmole) of (56) in 20 mL of NH3 /MeOH was stirred in a sealed flask at room temperature for 5 hr. Volatile materials were removed by evaporation. The residue was recrystallized from MeOH to give 337 mg (2 crops, 76%) of 57. Its 1H NMR spectrum was identical to that of (57) prepared by a direct bromination; see Method B.

WORKUP

后处理

  1. customVolatile materials were removed by evaporation
  2. customThe residue was recrystallized from MeOH