4-Fluorobenzaldehyde → 4-{2-[Methyl(pyridin-2-yl)amino]ethoxy}benzaldehyde

HRID 263990Notes

Reaction equation

[CH3:1][N:2]([CH2:9][CH2:10][OH:11])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.F[C:13]1[CH:20]=[CH:19][C:16]([CH:17]=[O:18])=[CH:15][CH:14]=1>>[CH3:1][N:2]([CH2:9][CH2:10][O:11][C:13]1[CH:20]=[CH:19][C:16]([CH:17]=[O:18])=[CH:15][CH:14]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1

Participants

Reactant 2

HCID 680234-Fluorobenzaldehyde

HCID 7374202-(N-Methyl-N-(2-pyridyl)amino)ethanol

Product 1

HCID 104225464-{2-[Methyl(pyridin-2-yl)amino]ethoxy}benzaldehyde

Procedure

The title compound was prepared from 2-(N-methyl-N-(2-pyridyl)amino)ethanol (8.9 g) and 4-fluorobenzaldehyde by a similar procedure to that described in Preparation 22.

Workup

customthat described in Preparation 22

Sources & evidence

ORD record: ord-e03d1c5d72e949e98f3b52a19cb73c73
Source dataset: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05646169

Reaction notes

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