化工社化工社 化学情報印刷レポート · 研究参考用
Thiazolidinedione → 5-(4-[2-(N-Methyl-N-(2-benzothiazolyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thiazolidinedione | HCID 5437 | — |
| 反応物 | Piperidinium acetate | HCID 3014295 | — |
| 反応物 | 4-[2-(N-Methyl-N-(2-benzothiazolyl)amino)ethoxy]benzaldehyde | HCID 10403243 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 5-(4-[2-(N-Methyl-N-(2-benzothiazolyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione | HCID 54092794 | — |
反応手順
A solution of 4-[2-(N-methyl-N-(2-benzothiazolyl)amino)ethoxy]benzaldehyde (1.9 g) and 2,4-thiazolidinedione (0.8 g) in toluene (100 ml) containing a catalytic quantity of piperidinium acetate was boiled under reflux in a Dean and Stark apparatus for 2 hours. The mixture was cooled and filtered and the filtered solid was dried to give the title compound (mp 219° C.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05646169 |
| 出典データセット | uspto-grants-1997_07 |
| ORD ID | ord-61cc735c0ba44c448618b73f5af63f7a |
| 出典メモ | uspto-grants-1997_07 |