HCID 22857780, compound → HCID 178418248, compound

HRID 2643Notes

Reaction equation

HRID 2643 reaction equation
[CH3:1][CH:2]([CH3:32])[CH2:3][CH2:4][C@H:5]1[CH2:10][CH2:9][C@H:8]([Si:11]2(C3C=CC=CC=3)[CH2:16][CH2:15][CH:14]([C:17]3[CH:22]=[C:21]([F:23])[C:20]([OH:24])=[C:19]([F:25])[CH:18]=3)[CH2:13][CH2:12]2)[CH2:7][CH2:6]1.[F:33][C@@H:34]([CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44])[CH2:35]O>>[CH3:1][CH:2]([CH3:32])[CH2:3][CH2:4][C@H:5]1[CH2:10][CH2:9][C@H:8]([Si@H:11]2[CH2:12][CH2:13][C@H:14]([C:17]3[CH:18]=[C:19]([F:25])[C:20]([O:24][CH2:35][C@H:34]([F:33])[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44])=[C:21]([F:23])[CH:22]=3)[CH2:15][CH2:16]2)[CH2:7][CH2:6]1

Participants

3

Reactant 2

HCID 22857780HCID 22857780, compoundHCID 178418315HCID 178418315, compound

Product 1

HCID 178418248HCID 178418248, compound

Procedure

The general procedure of Example 1 was repeated using 4-(4-(trans-4-(3-methylbutyl)cyclohexyl)-4-phenyl-4-silacyclohexyl)-2,6-difluorophenol and (S)-2-fluoro-1-decanol, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-89dee9eba1ca4a43a70edd6d797697e9
Source dataset
uspto-grants-1998_03
Patent number
US05730902

Reaction notes

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