HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22859999, compound → HCID 22860032, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22859999 | HCID 22859999 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 22860032 | HCID 22860032 | — |
Reaction Steps
A solution of N-benzyloxy-2(R)-[(4-methoxybenzenesulfonyl)(benzyl)amino]-3-hydroxy-4-methylpentanamide (125 mg) in ethanol (100 ml) is hydrogenated in the presence of 5% palladium on charcoal (100 mg) at room temperature and atmospheric pressure to yield N-hydroxy-2(R)-[(4-methoxybenzenesulfonyl)(benzyl)amino]-3-hydroxy-4-methyl-pentanamide, m.p. 81°-82° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05646167 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-68e9e9e54ea74909833c789016ef91f5 |
| Source note | uspto-grants-1997_07 |