(S)-2-fluorooctane-1-ol → HCID 178418449, compound

HRID 2644Notes

Reaction equation

HRID 2644 reaction equation
[CH2:1]([Si:4]1(C2C=CC=CC=2)[CH2:9][CH2:8][CH:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[C:20]([F:22])[C:19]([OH:23])=[C:18]([F:24])[CH:17]=3)=[CH:12][CH:11]=2)[CH2:6][CH2:5]1)[CH2:2][CH3:3].[F:31][C@@H:32]([CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40])[CH2:33]O>>[CH2:1]([Si@H:4]1[CH2:9][CH2:8][C@H:7]([C:10]2[CH:11]=[CH:12][C:13]([C:16]3[CH:21]=[C:20]([F:22])[C:19]([O:23][CH2:33][C@H:32]([F:31])[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40])=[C:18]([F:24])[CH:17]=3)=[CH:14][CH:15]=2)[CH2:6][CH2:5]1)[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 11137325(S)-2-fluorooctane-1-olHCID 224374624-(4-(4-n-Propyl-4-phenyl-4-silacyclohexyl)phenyl)-2,6-difluorophenol

Product 1

HCID 178418449HCID 178418449, compound

Procedure

The general procedure of Example 1 was repeated using 4-(4-(4-n-propyl-4-phenyl-4-silacyclohexyl)phenyl) -2,6-difluorophenol and (S)-2-fluoro-1-octanol, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-f51cb37f4fa54c6b91257cdc5aa7389e
Source dataset
uspto-grants-1998_03
Patent number
US05730902

Reaction notes

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