(R)-(+)-2-fluorooctanol → HCID 178418409, compound

HRID 2646Notes

Reaction equation

HRID 2646 reaction equation
C([Si:10]1(C2C=CC=CC=2)[CH2:15][CH2:14][CH:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]3[CH:27]=[C:26]([F:28])[C:25]([OH:29])=[C:24]([F:30])[CH:23]=3)=[CH:18][CH:17]=2)[CH2:12][CH2:11]1)CCCCCCCC.[F:37][C@H:38]([CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46])[CH2:39]O>>[CH2:11]([Si@H:10]1[CH2:11][CH2:12][C@H:13]([C:16]2[CH:17]=[CH:18][C:19]([C:22]3[CH:27]=[C:26]([F:28])[C:25]([O:29][CH2:39][C@@H:38]([F:37])[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46])=[C:24]([F:30])[CH:23]=3)=[CH:20][CH:21]=2)[CH2:14][CH2:15]1)[CH2:12][CH2:13][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

Participants

3

Reactant 2

HCID 10855629(R)-(+)-2-fluorooctanolHCID 22437473HCID 22437473, compound

Product 1

HCID 178418409HCID 178418409, compound

Procedure

The general procedure of Example 1 was repeated using 4-(4-(4-n-nonyl-4-phenyl-4-silacyclohexyl)phenyl) -2,6-difluorophenol and (R)-2-fluoro-1-octanol, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-88408290ebb7421ba1638c2e701191bf
Source dataset
uspto-grants-1998_03
Patent number
US05730902

Reaction notes

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