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HRID264623

反应详情

EQUATION

反应方程式

HRID 264623 的结构方程式

REACTANTS

反应物

2
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：O=C(Cc1ccc(Cl)cc1)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1
HCID57287847

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Cc1ccc(Cl)cc1)N1CC[C@H](NCc2ccnc3ccccc23)C[C@H]1Cc1ccccc1
HCID57237934

未命名化合物

PROCEDURE

实验过程

256 mg (0.441 mmol) of (2R*,4S*)-2-benzyl-1-(4-chlorophenylacetyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine are reacted with 66 mg (1.76 mmol) of sodium borohydride in analogoy to Example 2. The title compound ##STR35## is obtained as white foam. TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.48, FD-MS: M+ =484.