Sodium borohydride → (2R*,4S*)-2-benzyl-1-(2-naphthylacetyl)-N-(4-quinolylmethyl)-4-piperidinamine

Participants

Reaction Steps

160 mg (0.269 mmol) of (2R*,4S*)-2-benzyl-1-(2-naphthylacetyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine are reacted with 42 mg (1.13 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR38## is obtained as colourless oil. TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.27, FD-MS: M+ =499.

Provenance & Evidence