Sodium borohydride → HCID 57089189, compound

Participants

Reaction Steps

0.25 1 g (0.460 mmol) of (2R*,4S*)-2-benzyl-1-(3-toluoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine is reacted with 0.070 g (1.84 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR71## is obtained (0.172 g, 83%) as white foam. TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.27, D-MS: M+ =449.

Provenance & Evidence