Sodium borohydride → HCID 57070170, compound

Participants

Reaction Steps

0.271 g (0.444 mmol) of (2R*,4S*)-2-benzyl-1-(3-bromobenzoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine is reacted with 0.067 g (1.78 mol) of sodium borohydride in analogy to Example 2. The title compound ##STR72## is obtained (0.212 g, 93%) as oil. TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.29, FD-MS: M+ =513, 515.

Provenance & Evidence