Sodium borohydride → HCID 44288789, compound

Participants

Reaction Steps

0.202 g (0.291 mmol) of (2R*,4S*)-2-benzyl-1-(4-chlorobenzoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine is reacted with 0.054 g (1.43 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR76## is obtained (0.136 g, 81%) as white foam. TLC: methylene chloride/methanol/conc. ammonia (1000:50:1) Rf =0.17, FD-MS: M+ =469, 471; IR: 3675, 1625, 1595, 1570 cm-1.

Provenance & Evidence