Sodium borohydride → HCID 57202634, compound

Participants

Reaction Steps

0.175 g (0.321 mmol) of (2R*,4S*)-2-benzyl-1-(4-methoxybenzoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine is reacted with 0.047 g (1.25 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR100## is obtained (0.100 g, 69%) as white foam. TLC:methylene chloride/methanol/conc. ammonia (1000:50:1) Rf =0.21, FD-MS:M+ =465; IR:1620 cm-1.

Provenance & Evidence