Aluminium lithium hydride → N-(4-Phenyl-n-butyl)-4a-(m-methoxyphenyl)-cis-decahydroisoquinoline

Participants

Reaction Steps

N-(4-Phenyl-n-butyl)-4a-(m-methoxyphenyl)-1,3-diketo-cis-decahydroisoquinoline (0.8 g) in anhydrous tetrahydrofuran was treated with 0.8 g of lithium aluminum hydride and refluxed overnight. The reaction mixture was worked up as indicated in Example 2-B to yield 0.7 g of an opaque oil which was evaporatively distilled, bp 80°-90°, and identified as N-(4-phenyl-n-butyl)-4a-(m-methoxyphenyl)-cis-decahydroisoquinoline.

Provenance & Evidence