HRID264740

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(NC(=O)c2ccccc2)nc1=O

HCID15484896

未命名化合物

结构：COc1cccc(C(Cl)(c2ccccc2)c2ccccc2)c1OC

HCID66624882

未命名化合物

PRODUCTS

生成物

结构：CCCCCO[C@@H]1[C@H](O)[C@@H](COC(c2ccccc2)(c2ccccc2)c2cccc(OC)c2OC)O[C@H]1n1ccc(NC(=O)c2ccccc2)nc1=O

HCID69941131

未命名化合物

收率 69.5%

PROCEDURE

实验过程

N4-Benzoyl-2'-O-pentylcytidine (3.0 g, 0.007 mol) was treated with dimethoxytrityl chloride (2.7 g, 1.1 eq) as per the procedure of Example 72 to give 3.5 g of pure product. Anal. Calcd. for C42H45N3O8.1/2H2O: C, 69.21; H, 6.36; N, 5.76. Found: C, 69.51; H, 6.30; N, 5.71.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a844bb9f7f164109b8cba5c31073b476
来源数据集: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05646265
来源说明: uspto-grants-1997_07

反应 SMILES

[C:1]([NH:9][C:10]1[CH:29]=[CH:28][N:13]([C@@H:14]2[O:27][C@H:24]([CH2:25][OH:26])[C@@H:22]([OH:23])[C@H:15]2[O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[C:12](=[O:30])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:31][O:32][C:33]1[C:34]([O:53][CH3:54])=[C:35]([CH:50]=[CH:51][CH:52]=1)[C:36](Cl)([C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)[C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1>>[C:1]([NH:9][C:10]1[CH:29]=[CH:28][N:13]([C@@H:14]2[O:27][C@H:24]([CH2:25][O:26][C:36]([C:43]3[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=3)([C:37]3[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=3)[C:35]3[CH:50]=[CH:51][CH:52]=[C:33]([O:32][CH3:31])[C:34]=3[O:53][CH3:54])[C@@H:22]([OH:23])[C@H:15]2[O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[C:12](=[O:30])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1