Lawesson's reagent → HCID 19037098, compound

Participants

Reaction Steps

227 mg of Lawesson's reagent was added to a mixture of 210 mg of N-(2-cyanoethyl)-6-pentafluoroethyl-2,2-dimethyl-2H-1-benzopyran-4-carbamide obtained according to Example 1 and 20 ml of benzene, and the resulting mixture was heated while refluxing for 1 hour. After concentrating the mixture under reduced pressure, the resulting residue was purified by silica gel column chromatography (a developing solution: methylene chloride) to obtain 180 mg of N-(2-cyanoethyl)-6-pentafluoroethyl-2,2-dimethyl-2H-1-benzopyran-4-carbothioamide.

Provenance & Evidence