HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-chloro-2,2-bis(fluoromethyl)-2H-1-benzopyran-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | ethyl 6-chloro-2,2-bis(fluoromethyl)-2H-1-benzopyran-4-carboxylate | HCID 19037051 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-chloro-2,2-bis(fluoromethyl)-2H-1-benzopyran-4-carboxylic acid | HCID 19037075 | 78.7% |
Reaction Steps
A mixture of 0.07 g of ethyl 6-chloro-2,2-bis(fluoromethyl)-2H-1-benzopyran-4-carboxylate, 0.05 g of KOH and 3 ml of ethyl alcohol was stirred at room temperature for 1 hour. Ice water and conc. HCl was added to the reaction mixture and precipitated crystals were collected by filtration to obtain 0.05 g of 6-chloro-2,2-bis(fluoromethyl)-2H-1-benzopyran-4-carboxylic acid with a melting point of 151°-152° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05646308 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-4fa8c74421374fc5810f31e8cd97a89a |
| Source note | uspto-grants-1997_07 |