反应详情

A solution of 2[N-(3-carbethoxypropyl)-isobutyramido]-4-methyloxazole (9.9 g., 0.035 mol.) prepared in a manner similar to that described in Example 44 was dissolved in ethanol (100 ml.) and N NaOH solution (35 ml.) and the solution was stirred for 20 hours at ambient temperature. The solution was evaporated and the residue was dissolved in water, washed with ether, acidified and extracted with ether. The extract was dried and evaporated and the residue was recrystallised from benzene-- petrol to give the product 5.1 g., m.p. 81°- 82° C.

1. customThe solution was evaporated
2. dissolutionthe residue was dissolved in water
3. washwashed with ether
4. extractionextracted with ether
5. customThe extract was dried
6. customevaporated
7. customthe residue was recrystallised from benzene-- petrol