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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 265053Generated: November 1, 2026

5-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetraazole → Dimethyl 2-butyl-1-{4-[2-(trityltetrazol-5-yl)phenyl]phenyl}methylimidazole-4,5-dicarboxylate

https://huagongshe.com/reaction/265053

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetraazoleHCID 10053461—
ReactantDimethyl 2-butyl-1H-imidazole-4,5-dicarboxylateHCID 14955796—
ProductDimethyl 2-butyl-1-{4-[2-(trityltetrazol-5-yl)phenyl]phenyl}methylimidazole-4,5-dicarboxylateHCID 1903614834.2%

Reaction Steps

Following a procedure similar to that described in Example 35(a), but using 0.50 g of dimethyl 2-butylimidazole-4,5-dicarboxylate (prepared as described in Preparation 4) and 1.17 g of 4-[2-(trityltetrazol-5-yl)phenyl]benzyl bromide, 0.51 g of the title compound was obtained as an amorphous solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05646171
Source datasetuspto-grants-1997_07
ORD IDord-663a7df66dbc471fbea04c40cfb2603e
Source noteuspto-grants-1997_07