HCID 54034490, compound → HCID 178418267, compound

HRID 2651Notes

Reaction equation

HRID 2651 reaction equation
Br[CH2:2][C@H:3]([F:10])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].FC(F)(F)S(O[C:17]1[C:22]([F:23])=[CH:21][C:20]([CH:24]2[CH2:29][CH2:28][Si:27]([CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][O:41][CH3:42])(C3C=CC=CC=3)[CH2:26][CH2:25]2)=[CH:19][C:18]=1[F:43])(=O)=O>>[CH3:42][O:41][CH2:40][CH2:39][CH2:38][CH2:37][CH2:36][Si@H:27]1[CH2:28][CH2:29][C@H:24]([C:20]2[CH:19]=[C:18]([F:43])[C:17]([CH2:2][C@H:3]([F:10])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9])=[C:22]([F:23])[CH:21]=2)[CH2:25][CH2:26]1

Participants

3

Reactant 2

HCID 54034490HCID 54034490, compoundHCID 54046112(R)-1-bromo-2-fluorooctane

Product 1

HCID 178418267HCID 178418267, compound

Procedure

The general procedure of Example 18 was repeated using (R)-1-bromo-2-fluorooctane and (2,6-difluoro-4-(4-(5-methoxypentyl)-4-phenyl-4-silacyclohexyl)phenyl) trifluoromethanesulfonate, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-b51b9188153b4471b5d5fb0de0258451
Source dataset
uspto-grants-1998_03
Patent number
US05730902

Reaction notes

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