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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 265163Generated: October 25, 2026

1,1,1-Trimethoxybutane → 2-propyl-1H-imidazole-4,5-dicarbonitrile

https://huagongshe.com/reaction/265163

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,1-TrimethoxybutaneHCID 123512—
ReactantDiaminomaleonitrileHCID 2723951—
Product2-propyl-1H-imidazole-4,5-dicarbonitrileHCID 276372178.9%

Reaction Steps

Following a procedure similar to that described in Preparation 1, but using 16.0 g of diaminomaleonitrile and 24 g of trimethyl orthobutyrate, 18.7 g of the title compound were obtained as crystals, melting at 141°-144° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05646171
Source datasetuspto-grants-1997_07
ORD IDord-4c96f6bfc5344a9db8bccc781f29ea19
Source noteuspto-grants-1997_07