HCID 19036218, compound → HCID 178441659, compound

HRID 265174Notes

Reaction equation

HRID 265174 reaction equation
OC(C1N=C(CCC)NC=1C(OCC)=O)C.[C:17]([C:20]1[N:21]=[C:22]([CH2:30][CH2:31][CH2:32][CH3:33])[NH:23][C:24]=1[C:25]([O:27][CH2:28][CH3:29])=[O:26])(=[O:19])[CH3:18]>>[CH2:30]([C:22]1[NH:23][C:24]([C:25]([O:27][CH2:28][CH3:29])=[O:26])=[C:20]([CH:17]([OH:19])[CH3:18])[N:21]=1)[CH2:31][CH2:32][CH3:33]

Participants

3

Reactant 2

HCID 19036218HCID 19036218, compoundHCID 178440097HCID 178440097, compound

Product 1

HCID 178441659HCID 178441659, compoundYield 85.2%

Procedure

Following a procedure similar to that described in Preparation 23(iii), but using 0.64 g of ethyl 4-acetyl -2-butylimidazole-5-carboxylate [prepared as described in step (ii) above], 0.55 g of the title compound was obtained as crystals, melting at 149° C.

Sources & evidence

ORD record
ord-5b5dc2dd51bf4821ba1a4515eafd2b4f
Source dataset
uspto-grants-1997_07
Patent number
US05646171

Reaction notes

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