HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 2-Propyl-4-pivaloylimidazole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 2-propyl-1H-imidazole-4,5-dicarbonitrile | HCID 2763721 | — |
| Reactant | HCID 178418310 | HCID 178418310 | — |
| Product | 2-Propyl-4-pivaloylimidazole-5-carbonitrile | HCID 178440144 | — |
Reaction Steps
Following a procedure similar to that described in Preparation 40, but using 3.2 g of 2-propylimidazole-4,5-dicarbonitrile (prepared as described in Preparation 10) and 33 ml of a 2M solution of t-butylmagnesium chloride in diethyl ether, 2.35 g of the title compound were obtained as crystals, melting at 176°-178° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05646171 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-fbb04630f653448c8d5a53857ce1386f |
| Source note | uspto-grants-1997_07 |